Journal of Chemistry / 2013 / Article / Tab 2

Research Article

In Vitro Antioxidant and Anticancer Activity of Flavonoid Fraction from the Aerial Parts of Cissus quadrangularis Linn. against Human Breast Carcinoma Cell Lines

Table 2

Free radicals scavenging property of ethanolic extract and isolated flavonoid fraction of Cissus quadrangularis Linn.

TestConcentration (µg/mL)Nitric oxide inhibition (%) DPPH radical inhibition (%)Hydroxyl radical inhibition (%)

Ethanol extract2534.15 ± 1.26**27.67 ± 1.17**36.57 ± 0.54**
5048.18 ± 0.36**38.05 ± .25**48.16 ± 1.40**
10051.84 ± 2.72**43.63 ± .58**53.32 ± 1.08**
20069.24 ± 1.96**61.80 ± 2.43**63.21 ± 1.72**
40074.32 ± 2.16**73.67 ± 0.35**78.96 ± 0.61**
IC5098 µg/mL125 µg/mL96 µg/mL

Flavonoid fraction532.58 ± 0.58**28.05 ± 1.20**35.45 ± 1.20**
1050.24 ± 3.28**45.23 ± 2.18**50.32 ± 1.50**
2067.38 ± 0.54**64.80 ± 1.43**62.24 ± 3.28**
4072.26 ± 0.86**73.67 ± 2.85**69.38 ± 0.54**
8082.89 ± 0.97**80.89 ± 1.40**79.26 ± 0.86**
IC5010 µg/mL12 µg/mL10 µg/mL

Standard quercetin528.30 ± 1.08**30.25 ± 0.47**34.25 ± 0.47**
1035.25 ± 0.47**41.10 ± 2.16**42.10 ± 3.16**
2044.10 ± 2.16**49.66 ± 1.12**48.66 ± 1.12**
4056.66 ± 1.12**67.09 ± 0.16**62.29 ± 0.54**
8071.79 ± 0.54**75.25 ± 2.47**73.25 ± 0.47**
IC5035 µg/mL25 µg/mL32 µg/mL

Values are mean ± SEM, statistical significant test for comparison was done by ANOVA, followed by Dunnet’s -test ( ). The values are when compared against standard.

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