Synthesis and Microbial Activity of Novel 3-Methyl-2-pyrazolin-5-one Derivatives

Table 4

Antimicrobial activity of prepared compounds.

Compd. no.	Inhibition zones (mm)
	Gram +ve bacteria		Gram −ve bacteria	Fungi
	B. subtilis	S. aureus	E. coli	C. albicans
2a	18	14	12	19
2b	13	10	11	20
3b	16	14	10	13
3c	14	12	15	11
4b	17	18	18	22
4c	22	17	16	20
5a	29	10	21	19
5b	23	10	11	18
5c	19	15	20	10
5d	23	10	19	25
5e	22	14	13	15
5f	20	18	22	13
Tetracycline	28	26	20	—
Nystatin	—	—	—	24