Preparation of New α-Aminophosphonate Derivatives by Kabachnik-Fields Reaction Using a Recyclable Catalyst

Table 1

Reaction time and percentage yield of 4 in different reaction conditions.

Entry	Catalyst used	Reaction condition	Reaction time	% yield	Reference
1	Al(H2PO4)3	Solvent-free/100°C	90 min	93	[39]
2	InCl3	THF/RT	11 h	92	[34]
3	BiCl3	CH3CN/reflux	6 h	92	[40]
4	FeCl3	THF/60°C	0.75 h	92	[41]
5	YbCl3	CH3CN/RT	24 h	93	[42]
6	In(OTf)3	THF/reflux	21 h	79	[43]
7	Ce(OTf)4	Solvent-free/50°C	20 min	94	[44]
8	Mg(ClO4)2	Solvent-free/80°C	5 h	99	[37]
9	CAN	Solvent-free/reflux	30 min	96	[46]
10	TaCl5-SiO2	CH2Cl2/RT	22 h	92	[47]
11	TiO2	Solvent-free/50°C	3.5 h	98	[50]
12	ZnO	Solvent-free/RT	9 h	90	[50]
13	NBS	Solvent-free/50°C	3 h	99	[50]
14	Silica sulfuric acid	CH3CN/RT	5 h	87	[49]
15	3D mesoporous aluminosilicate nanocage	CH3CN/80°C	4 h	86	[50]
16	Cu(3,4-tmtppa)(MeSO4)4	H2O/80°C	0.5 h	96	[50]
17	Β-CD	H2O/reflux	24 h	61	[50]
18	CaCl2	Solvent-free/60°C	3 h	90	[48]
19	PPh3	Solvent-free/60°C	1 h	87	[48]
20	NbCl5	Solvent-free/50°C	30 min	95	[50]
21	—	Toluene/reflux	5 h	81	Present work
22	—	Solvent-free/mw	1 min	87	Present work
23	Amberlyst-IRC 748	Toluene/reflux	30 min	93	Present work