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Journal of Chemistry
Volume 2013, Article ID 265107, 7 pages
http://dx.doi.org/10.1155/2013/265107
Research Article

Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene

Department of Chemistry, Sahyadri Science College (Autonomous), Kuvempu University, Shimoga-577203, Karnataka, India

Received 22 June 2012; Revised 10 August 2012; Accepted 10 August 2012

Academic Editor: Narcis Avarvari

Copyright © 2013 G. Krishnamurthy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Zinc(II) halides and perchlorate react with 1,4-bis(benzimidazol-2-yl)benzene (L) in 1 : 2 molar ratio in n-butanol/2-methoxy ethanol (10 mL) at refluxing temperature to produce white/pale yellow-colored complexes of the formulae [ZnCl2L]H2O, [ZnBr2L]3H2O, and [Zn(OClO3)2L]HOCH2CH2CH2CH3. Zinc(II) iodide also reacts with L in 1 : 2 molar ratio in n-butanol (HOCH2CH2CH2CH3) to yield white-colored complex of the formula [ZnL2(OCH2CH2CH2CH3)2]. The complexes were characterized by elemental analysis, molar conductance measurements, thermal analysis, and IR, 1H-, 13C-NMR spectral studies. The complexes showed significant anthelmintic activity. The minimum energy configuration has been obtained for the zinc complexes using molecular modeling Pro Plus; a tool developed by ChemSW, inc, USA.