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Journal of Chemistry
Volume 2013, Article ID 275698, 9 pages
Research Article

Chemical Composition and Cytotoxic and Antioxidant Activities of Satureja montana L. Essential Oil and Its Antibacterial Potential against Salmonella Spp. Strains

1Laboratory of Analysis, Treatment and Valorisation of Environmental Pollution and Products, Faculty of Pharmacy, Tunisia City Avicenne, 5000 Monastir, Tunisia
2UR Study & Management of Urban and Coastal Environments, LARSEN, National Engineering School, BP 1173, 3038 Sfax, Tunisia
3Laboratory of Biochemistry, Faculty of Medicine, 5019 Monastir, Tunisia
4Range Ecology Laboratory, Arid Land Institute of Medenine, 4119 Medenine, Tunisia

Received 2 May 2013; Revised 28 June 2013; Accepted 7 July 2013

Academic Editor: Serkos A. Haroutounian

Copyright © 2013 Hanene Miladi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The present study describes chemical composition as well as cytotoxic, antioxidant, and antimicrobial activities of winter savory Satureja montana L. essential oil (EO). The plant was collected from south France mountain, and its EO was extracted by hydrodistillation (HD) and analysed by gas chromatography/mass spectrometry (GC/MS). Thirty-two compounds were identified accounting for 99.85% of the total oil, where oxygenated monoterpenes constituted the main chemical class (59.11%). The oil was dominated by carvacrol (53.35%), -terpinene (13.54%), and the monoterpenic hydrocarbons p-cymene (13.03%). Moreover, S. montana L. EO exhibited high antibacterial activities with strong effectiveness against several pathogenic food isolated Salmonella spp. including S. enteritidis with a diameter of inhibition zones growth ranging from 21 to 51 mm and MIC and MBC values ranging from 0.39–1.56 mg/mL to 0.39–3.12 mg/mL, respectively. Furthermore, the S. montana L. EO was investigated for its cytotoxic and antioxidant activities. The results revealed a significant cytotoxic effect of S. montana L. EO against A549 cell line and an important antioxidant activity. These findings suggest that S. montana L. EO may be considered as an interesting source of components used as potent agents in food preservation and for therapeutic or nutraceutical industries.