A Convenient Synthesis of C-3-Aryloxymethyl Imidazo[1,2-𝑎]Pyridine Derivatives

Table 1

Scope of the synthesis of C-3-aryl ether substituted 2-phenyl imidazo[1,2-a]pyridines 10a–10m. ^aReaction conditions: Tosylhydrazone 8 (1.0 mmol), phenol (2.0 mmol), K₂CO₃ (3.5 mmol) dioxane (4.0 mL), 110°C, 12 h. ^byield refers to pure and isolated.

Serial no.	Ether	Yield (%)	Serial no.	Ether	Yield (%)
1		76	7		95
2		87	8		64
3		88	9		81
4		84	10		84
5		73	11		76
6		79	12		63