Research Article
Sparfloxacin-Metal Complexes as Urease Inhibitors: Their Synthesis, Characterization, Antimicrobial, and Antienzymatic Evaluation
Table 7
Enzymatic activities of SPFX metal complexes.
| | Enzymes | Urease | Carbonic anhydrase | α-Chymotrypsin | | Compounds | Inhibition (%) | IC50 ± SEM (μm) | Inhibition (%) | IC50 ± SEM (μm) | Inhibition (%) | IC50 ± SEM (μm) |
| | SPAR | 47.3 | — | 26.00 | — | 21.1 | — | | S12 | 67.20 | 128.53 ± 0.11 | 11.30 | — | 33.5 | — | | S13 | 88.30 | 316.2 ± 0.60 | 10.00 | — | 25.1 | — | | S14 | 81.20 | 169.96 ± 0.26 | — | — | 19.6 | — | | S15 | 89.20 | 145.13 ± 0.09 | 3.70 | — | 22.9 | — | | Standard | 98.2 | 21.00 ± 0.11 | 78.1 | 0.30 ± 0.0006 | 98.1 | 5.70 ± 0.13 |
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