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Journal of Chemistry
Volume 2013, Article ID 345059, 6 pages
Research Article

Effect of Achyranthes aspera Root and Terminalia arjuna Bark on Aerotolerant Responses in Streptococcus mutans

Department of Siddha Medicine, Faculty of Sciences, Tamil University, Thanjavur 613007, India

Received 29 November 2011; Revised 7 July 2012; Accepted 8 July 2012

Academic Editor: Lorenzo Cerretani

Copyright © 2013 C. Mahima and V. Hazeena Begum. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In the present study, the effect of hydroalcoholic extract of Achyranthes aspera root (AAR) and Terminalia arjuna bark (TAB) on the aerotolerant capacities of Streptococcus mutans was examined. AAR and TAB extracts were found to inhibit the prime antioxidant enzymes like manganese superoxide dismutase (MnSOD), NADH oxidases, and glutathione peroxidase (GPx), altering the aerotolerant responses in S. mutans. Consequently, S. mutans are unable to withstand the oxidative stress and thus are made more susceptible to the antimicrobial activity.