Novel LC Method Development and Validation for Simultaneous Determination of Montelukast and Doxofylline in Bulk and Pharmaceutical Dosage Forms

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left"></td><td align="center">    Retention Time %RSD</td><td align="center">Area %RSD</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left">Day 1 &amp; analyst 1</td><td align="center"></td><td align="center"></td></tr><tr><td align="left"> Montelukast</td><td align="center">0.29</td><td align="center">0.8</td></tr><tr><td align="left"> Doxofylline</td><td align="center">0.12</td><td align="center">0.34</td></tr><tr><td align="left">Day 2 &amp; analyst 2</td><td align="center"></td><td align="center"></td></tr><tr><td align="left"> Montelukast</td><td align="center">0.09</td><td align="center">0.49</td></tr><tr><td align="left"> Doxofylline</td><td align="center">0.11</td><td align="center">0.41</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

%RSD of the drugs on different days and different analysts.

Journal of Chemistry

tab5

Table 5

Table 5: Novel LC Method Development and Validation for Simultaneous Determination of Montelukast and Doxofylline in Bulk and Pharmaceutical Dosage Forms 

Table 5 | Novel LC Method Development and Validation for Simultaneous Determination of Montelukast and Doxofylline in Bulk and Pharmaceutical Dosage Forms 