Journal of Chemistry / 2013 / Article / Tab 1

Research Article

The Reaction of Cyclopentanone with Cyanomethylene Reagents: Novel Synthesis of Pyrazole, Thiophene, and Pyridazine Derivatives

Table 1

Physical and microanalysis of the newly synthesized compounds 3a16b.

Comp. no. m.p. Yield (%)Solvent of crystallizationMolecular formulaeC%H%N%S%

3a148–15078EthanolC8H8N2
132.16
72.706.1021.20
3b100–11281EthanolC10H13NO2
179.22
67.127.217.79
5a98–10078EthanolC14H12N4
236.27
71.025.2212.59
5b60–6286EthanolC14H11ClN4
270.72
62.084.3920.93
5c88–9090EthanolC16H17N3O2 283.3367.665.9314.95
5d58–6077EthanolC16H16ClN3O2
317.77
60.385.1113.08
7a70–7278EthanolC14H18N6
270.33
62.366.8331.11
7b80–8282EthanolC20H22N6
346.43
69.636.5524.07
7c68–7078EthanolC14H17N5O 
271.32
61.776.4925.64
7d78–8080EthanolC20H21N5O 
347.41
69.256.2719.84
9a98–10078EthanolC15H12N2
220.27
81.675.3312.57
9b40–4270EthanolC17H17NO2
267.32
76.516.585.33
11a98–10082EthanolC17H13N3
259.31
78.634.9316.08
11b80–8282EthanolC19H18N2O2
306.14
74.625.869.08
11c68–7082EthanolC19H18N2O2
306.14
74.525.729.22
11d58–6077EthanolC21H23NO4
353.41
71.586.624.25
13a88–9080EthanolC8H8N2S 
164.23
58.514.9117.0619.52
13b70–7272EthanolC10H13NO2S 
211.28
58.856.206.6315.18
14a120–12286EthanolC14H12N4S 
268.34
62.744.7520.6712.28
14b78–8169EthanolC16H17N3O2S 
315.39
61.315.6713.1510.06
15a90–92721,4-dioxaneC16H14N4OS 
310.37
62.034.7417.9910.48
15b68–70831,4-dioxaneC18H19N3O3S   
357.43
60.585.5211.84 9.32
16a78–80801,4-dioxaneC14H12N4
236.27
71.274.9223.88
16b70–7277 1,4-dioxaneC14H11N3O 
237.26
70.644.8317.93

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