Cyanuric Chloride-Catalyzed Michael Addition of Indoles to Nitroolefins under Solvent-Free Conditions

Table 1

Synthesis of 3-(2-nitro-1-phenylethyl)-1H-indole under various conditions^a.

Entry	TCT (mol%)	T. (°C)	Time (min)	Yield (%)^b
1	0	70	120	63
2	5	70	45	88
3	10	70	30	97
4	15	70	30	96
5	10	25	120	63
6	10	40	60	71
7	10	50	45	85
8	10	60	30	90
9	10	80	30	96
10	10	90	30	96

^aReaction conditions: indole (1 mmol); β-nitrostyrene (1 mmol); neat.
^bIsolated yield.