Cyanuric Chloride-Catalyzed Michael Addition of Indoles to Nitroolefins under Solvent-Free Conditions

Table 2

Michael addition of indoles to nitroolefins catalyzed by TCT under solvent-free condition.

Entry	Indoles	Nitroolefins	Products	Time (min)	Yield; (%)^b	m.p. (°C); (lit.)
1				30	97	101-102 (99-100) [23]
2				30	93	liquid; (liquid) [28]
3				30	94	144–146; (146-147) [23]
4				60	89	142-143; (144–146) [28]
5				30	95	100–102; (99–101) [28]
6				20	96	75-76; (77-78) [23]
7				120	87	130–132; (131–133) [23]
8				45	92	143-144; (142) [20]
9				30	93	Semisolid (semisolid) [20]
10				20	98	144-145; (145–147) [28]
11				30	92	70-71; (67-68) [17]
12				30	90	85-86; (86-87) [23]
13				60	95	98-99; (95–97) [17]
14				60	89	100-101; (102-103) [23]
15				45	94	129–131; (130-131) [23]
16				60	88	113–115; (112–114) [17]
17				45	90	106-107; (107-108) [17]
18				90	89	141–143; (143–145) [28]

^aReaction conditions: indoles (1 mmol); nitroolefins (1 mmol); TCT (0.1 mmol); neat; 70°C.
^bIsolated yield.