One-Pot Solvent-Free Three-Component Synthesis of Conjugated Enaminones Containing Three Alkyl Carboxylate Groups

Table 1

The reaction of primary amine, alkyl acetoacetate, and dialkyl acetylenedicarboxylate.

Product 4	R	R′	R′′	Yield % 4
a	n-Pr	Me	Me	80
b	n-Pr	Me	Et	85
c	n-Pr	Et	Me	84
d	n-Pr	Et	Et	85
e	^iPr	Me	Me	86
f	^iPr	Me	Et	90
g	^iPr	Et	Me	87
h	Allyl	Me	Me	94
i	Allyl	Et	Me	90