Extractive Spectrophotometric Method for the Determination of Lamivudine and Zidovudine in Pharmaceutical Preparations Using Bromocresol Purple

Table 2

Determination of LVD and ZVD in dosage forms by standard addition method.

	Amount of taken drug (μg)	Amount of pure drug added (μg)	Total amount found (μg)^a; (Mean ± S.D.^b)	RSD (%)	Recovery of pure drug added (%)
LVD	100	25	125.24 ± 1.28	1.02	100.96
	100	100	200.35 ± 1.01	0.50	100.35
	100	150	251.25 ± 2.21	0.88	100.83
ZVD	100	50	150.02 ± 1.02	0.68	100.04
	100	100	201.28 ± 1.24	0.62	101.28
	100	200	300.12 ± 2.08	0.69	100.06

aFive independent analyses.
^bStandard deviation.