Table 3: Determination of LVD and ZVD in dosage forms by the proposed and reference methods.

Statistical valueLVDZVD
Proposed methodaReference method [7]Proposed methodbReference method [6]

Meanc100.12100.13249.57249.93
Recovery (%)100.12100.1399.8399.97
RSD (%)0.150.1980.330.15
-test of significanced0.0030.0088
-test of significanced1.720.209

Zeffix (containing 100 mg of lamivudine per tablet).
bRetrovir (containing 250 mg of zidovudine) per capsules.
cFive independent analyses.
d = 0.05, , .