Journal of Chemistry / 2013 / Article / Tab 1

Research Article

Cellulose-Sulfuric Acid as an Efficient Biosupported Catalyst in One-Pot Synthesis of Novel Heteroaryl Substituted 1,4-Dihydropyridines

Table 1

Synthesis of heteroaryl substituted 1,4-dihydropyridines in the presence of cellulose-sulfuric acid catalyst.

EntryaAr 2Time (min)ProductYield (%)b

aPhDimedone42 (120)c5a90 (75)c
b -NO2C6H4Dimedone455b95
c -ClC6H4Dimedone405c94
dPh1,3-Cyclohexanedione43 (125)c5d88 (72)c
e -NO2C6H41,3-Cyclohexanedione455e87
f -ClC6H41,3-Cyclohexanedione425f86
gPh1,3-Indanedione39 (120)c5g90 (75)c
h -NO2C6H41,3-Indanedione415h86
i -ClC6H41,3-Indanedione375i85

All products were characterized by 1H NMR, 13C NMR, and IR data.
bIsolated yields.
cMeasured in the absence of the catalyst.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.