Table of Contents Author Guidelines Submit a Manuscript
Journal of Chemistry
Volume 2013, Article ID 523193, 4 pages
http://dx.doi.org/10.1155/2013/523193
Research Article

Validated Spectrophotometric Methods for the Determination of Mycophenolate: An Anti-Neoplastic Agent in Bulk and Pharmaceutical Dosage Forms

1Department of Pharmaceutical Analysis and Quality Assurance, Roland Institute of Pharmaceutical Sciences, Berhampur 760010, India
2Department of Pharmaceutical Analysis and Quality Assurance, Royal College of Pharmacy and Health Sciences, Berhampur 760002, India
3Department of Pharmaceutical Analysis and Quality Assurance, GITAM Institute of Pharmacy, GITAM University, Visakhapatnam 530045, India

Received 28 November 2011; Revised 16 May 2012; Accepted 17 May 2012

Academic Editor: Irene Panderi

Copyright © 2013 A. Narendra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. Hosotsubo, S. Takahara, Y. Kokado et al., “Rapid and simple determination of mycophenolic acid in human plasma by ion-pair RP-LC with fluorescence detection,” Journal of Pharmaceutical and Biomedical Analysis, vol. 24, no. 4, pp. 555–560, 2001. View at Publisher · View at Google Scholar · View at Scopus
  2. J. F. Gummert, U. Christians, M. Barten, H. Silva, and R. E. Morris, “High-performance liquid chromatographic assay with a simple extraction procedure for sensitive quantification of mycophenolic acid in rat and human plasma,” Journal of Chromatography B, vol. 721, no. 2, pp. 321–326, 1999. View at Publisher · View at Google Scholar · View at Scopus
  3. D. Teshima, N. Kitagawa, K. Otsubo, K. Makino, Y. Itoh, and R. Oishi, “Simple determination of mycophenolic acid in human serum by column-switching high-performance liquid chromatography,” Journal of Chromatography B, vol. 780, no. 1, pp. 21–26, 2002. View at Google Scholar · View at Scopus
  4. C. G. Zambonin, A. Aresta, and F. Palmisano, “Determination of the immunosuppressant mycophenolic acid in human serum by solid-phase microextraction coupled to liquid chromatography,” Journal of Chromatography B, vol. 806, no. 2, pp. 89–93, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Pastore, A. Lo Russo, F. Piemonte, L. Mannucci, and G. Federici, “Rapid determination of mycophenolic acid in plasma by reversed-phase high-performance liquid chromatography,” Journal of Chromatography B, vol. 776, no. 2, pp. 251–254, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. N. Sugioka, H. Odani, T. Ohata, H. Kishimoto, T. Yasumura, and K. Takada, “Determination of a new immunosuppressant, mycophenolate mofetil, and its active metabolite, mycophenolic acid, in rat and human body fluids by high-performance liquid chromatography,” Journal of Chromatography B, vol. 654, pp. 249–256, 1994. View at Google Scholar
  7. K. Na-Bangchang, O. Supasyndh, T. Supaporn, V. Banmairuroi, and J. Karbwang, “Simple and sensitive high-performance liquid chromatographic method for the determination of mycophenolic acid in plasma,” Journal of Chromatography B, vol. 738, no. 1, pp. 169–173, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. D. A. Saunders, “Author index vol. 690,” Journal of Chromatography B, vol. 704, no. 1-2, pp. 379–382, 1997. View at Publisher · View at Google Scholar
  9. K. Wiwattanawongsa, E. L. Heinzen, D. C. Kemp, R. E. Dupuis, and P. C. Smith, “Determination of mycophenolic acid and its phenol glucuronide metabolite in human plasma and urine by high-performance liquid chromatography,” Journal of Chromatography B, vol. 763, no. 1-2, pp. 35–45, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. V. Srivatsan, A. K. Dasgupta, P. Kale et al., “Determination of mycophenolic acid in human plasma by high-performance liquid chromatography,” Journal of Chromatography A, vol. 1031, no. 1-2, pp. 259–264, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. M. A. Barzoki, M. Rouini, K. Gholami, M. Lessan-Pezeshki, and S. Rezaee, “Determination of mycophenolic acid in human plasma by high-performance liquid chromatography,” Daru, vol. 13, no. 3, pp. 120–126, 2005. View at Google Scholar · View at Scopus
  12. S. Gopalakrishnan, E. Vadivei, P. Krishnaveni, and B. Jeyashree, “A novel reverse phase-HPLC method development and validation of Mycophenolate sodium-an immunosuppressant drug,” Research Journal of Pharmaceutical, Biological and Chemical Sciences, vol. 1, no. 4, pp. 200–207, 2010. View at Google Scholar · View at Scopus
  13. M. O. Benoit-Biancamano, P. Caron, É. Lévesque, R. Delage, F. Couture, and C. Guillemette, “Sensitive high-performance liquid chromatography-tandem mass spectrometry method for quantitative analysis of mycophenolic acid and its glucuronide metabolites in human plasma and urine,” Journal of Chromatography B, vol. 858, no. 1-2, pp. 159–167, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. A. L. Rao, P. V. Srinivas, and J. V. L. N. S. Rao, “A new validated RP-HPLC method for the estimation of mycophenolate mofetil in pure and tablet dosage form,” Journal of Pharmaceutical Research and Health Care, vol. 2, no. 3, pp. 266–269, 2010. View at Google Scholar · View at Scopus
  15. H. Benech, S. Hascoet, V. Furlan, A. Pruvost, and A. Durrbach, “Development and validation of an LC/MS/MS assay for mycophenolic acid in human peripheral blood mononuclear cells,” Journal of Chromatography B, vol. 853, no. 1-2, pp. 168–174, 2007. View at Publisher · View at Google Scholar
  16. S. P. Verma, S. J. Gilani, I. Bala et al., “Validated, stability indicating HPTLC method for the determination of mycophenolate mofetil in human plasma,” Current Analytical Chemistry, vol. 7, no. 3, pp. 216–219, 2011. View at Google Scholar · View at Scopus
  17. S. Verma, H. Gupta, O. Alam, P. Mullick, N. Siddiqui, and S. A. Khan, “Spectrophotometric methods for the estimation of mycophenolate mofetil,” Journal of Applied Spectroscopy, vol. 76, no. 6, pp. 876–882, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. F. E. Gainer and H. J. Wesselman, “GLC of mycophenolic acid and related compounds,” Journal of Pharmaceutical Sciences, vol. 59, no. 8, pp. 1157–1159, 1970. View at Google Scholar · View at Scopus
  19. S. K. Acharjya, A. Sahu, S. Das, P. Sagar, and M. M. Annapurna, “Spectrophotometric methods for the determination of mesalamine in bulk and pharmaceutical dosage forms,” Journal of Pharmaceutical Research, vol. 1, no. 1, pp. 63–67, 2010. View at Google Scholar
  20. ICH Steering Committee, “Validation of analytical procedures: methodology,” in Proceedings of the International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use, ICH Steering Committee, November 1996.
  21. A. H. Beckett and J. B. Stenlake, Practical Pharmaceutical Chemistry Edition, Part II, 4th edition, 2005.