Synthesis, Antioxidant, Antimicrobial, Antimycobacterial, and Cytotoxic Activities of Azetidinone and Thiazolidinone Moieties Linked to Indole Nucleus

Table 1

Antimicrobial activity of synthesized compounds (3–5).

Compounds	Antibacterial activity (zone of inhibition in mm)				Antifungal activity (zone of inhibition in mm)
	EC	SA	KP	PA	AO	AN	AF	AT
3a	15	11	13	12	14	14	15	13
3b	12	16	15	10	14	13	11	12
3c	11	10	12	13	12	11	16	15
4a	20	21	21	22	19	15	16	12
4b	12	13	10	11	15	10	15	14
4c	13	20	09	09	16	13	18	20
5a	14	18	20	18	20	19	19	18
5b	15	12	10	10	11	13	16	13
5c	16	10	13	13	13	16	15	16
Gentamycin	26	25	24	25	—	—	—	—
Fluconazole	—	—	—	—	22	22	21	20

Data represented is the mean of three replicates.
EC: Escherichia coli (MTCC-723); SA: Staphylococcus aureus (ATCC-29513); KP: Klebsiella pneumonia (NCTC-13368); PA: Pseudomonas aeruginosa (MTCC-1688); AO: Aspergillus oryzae (MTCC-3567^T); AN: Aspergillus niger (MTCC-281); AF: Aspergillus flavus (MTCC-1973); AT: Aspergillus terreus (MTCC-1782).