Exploring QSAR for Antimalarial Activities and Drug Distribution within Blood of a Series of 4-Aminoquinoline Drugs Using Genetic-MLR

Table 13

Evaluation of the prediction ability of the MLR models in the external validation set for 𝑅_𝑏.

	Training set				Test set
log 𝑅𝑏	𝑅^2	𝑅^2adj	RMSE	𝐹	𝑅^2𝑝𝑟𝑒𝑑	RMSE
B/P (1 μM)	0.89	0.83	0.05	14.57	0.93	0.06
B/P (10 μM)	0.87	0.80	0.11	12.03	0.84	0.09