The Inhibitory Effects of Aqueous Extract from Guava Twigs, Psidium guajava L., on Mutation and Oxidative Damage

Table 5

The mutagenicity of the aqueous extract of guava twigs (GTE) toward S. typhimurium TA98 and TA100 with and without S9 mix.

Sample (mg/plate)	His^+ revertants/plate (% of spontaneous)
	TA98	TA100
Spontaneous group	42 ± 2 (100)^a	194 ± 9 (100)^a
2	40 ± 5 (95)^a	186 ± 6 (96)^a
5	41 ± 3 (98)^a	177 ± 14 (91)^a
10	35 ± 3 (83)^a	175 ± 11 (90)^a
	TA98 + S9	TA100 + S9
Spontaneous group	27 ± 2 (100)^a	134 ± 5 (100)^a
2	25 ± 2 (93)^a	142 ± 8 (106)^a
5	27 ± 3 (100)^a	133 ± 7 (99)^a
10	24 ± 2 (89)^a	128 ± 9 (96)^a

Data represent means ± SD for 𝑛=3. Values with different superscripts in a column are significantly different (𝑃<0.05). % of spontaneous = ((no. of his⁺revertants in the presence of sample)/(no. of spontaneous revertants)) × 100. The number of spontaneous revertants was determined without samples and mutagens.