Validation of Quetiapine Fumarate in Pharmaceutical Dosage by Reverse-Phase HPLC with Internal Standard Method

Table 6

Short-term, long-term, and autosampler stability of quetiapine fumarate.

Nominal concentration
	5.12×10^−3 g/Lt	15.06×10^−3 g/Lt	40.16×10^−3 g/Lt
Short-term stability (12 hrs)
Mean (𝑛=3)	185884	512701	1273781
S.D	1239.619	2388.92	2057.69
R.S.D	0.6669	0.47	0.16
Recovery (%)	100.38	100.77	98.52
Autosampler stability (24 hrs)
Mean (𝑛=3)	200490	5069977	1281959
S.D	813.61	3132.07	6885.33
R.S.D	0.41	0.62	0.54
Recovery (%)	100.00	100.19	98.31