Journal of Chemistry / 2013 / Article / Tab 2

Research Article

A Green and Efficient Method for the Preparation of 3,4-Dihydropyrimidin-2(1H)-ones Using Quaternary Ammonium-Treated Clay in Water

Table 2

Synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by CTAB-modified clay.

EntryRR1Time (h)Yield (%)a,b

4aHCH30.589
4b4-NO2CH30.7591
4c3-NO2CH31.092
4d4-OHCH30.7587
4e2-MeOCH31.088
4f4-ClCH30.585
4g2-ClCH31.0 88
4h4-CH3CH30.589
4iHEtO0.7589
4j4-FEtO0.7585
4k4-CH3EtO0.590
4l4-MeOEtO0.7587
4m4-ClEtO0.590
4n2-ClEtO0.7586
4o4-NMe2EtO0.7584

Products are known and were identified by comparison of their physical and spectral data with those of authentic samples [1822].
bIsolated yields.