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Journal of Chemistry
Volume 2013 (2013), Article ID 634510, 5 pages
Research Article

A Simple and Green Protocol for 2H-Indazolo[2,1-b]phthalazine-triones Using Grinding Method

1Tianjin Entry-Exit Inspection and Quarantine Bureau, Tianjin 300457, China
2Tianjin Lishen Battery Joint-Stock Co., Ltd., Tianjin 300384, China

Received 7 May 2013; Revised 6 June 2013; Accepted 6 June 2013

Academic Editor: A. M. S. Silva

Copyright © 2013 Xiao-chuan Jia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A robust, facile, and solvent-free route for the three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones in the presence of a catalytic amount of p-toluene sulfonic acid utilizing grinding has been developed. Short reaction time, simple operation, and high yields are the advantages of this protocol.