Synthesis and Biological Activity of 2,5-Bisubstituted Derivatives of 1,3,4-Thiadiazol-2,5-dithiol

Table 1

Antioxidant activity of compounds (23–26, 28, and 29).

Compound number	Compound	𝐶MDA, nmol/L; (30 min incubation)	Decrease of 𝐶MDA in comparison to control level, %
Control	—	30,01	—
Ionol	2,6-Di-tert-butylphenol	9,32	68,94
23	1,3,4-Thiadiazol-2,5-disulfonic acid	15,16	50,52
24	Piperidine salt	4,58	84,74
25	Morpholine salt	14,68	51,08
26	Anabasine salt	20,68	31,09
28	Cytisine salt	14,68	51,08
29	l-ephedrine salt	14,05	53,18