Comparative Evaluation of the Antidiabetic Effects of Different Parts of Cassia fistula Linn, a Southeast Asian Plant

Table 4

Effect of methanolic and aqueous bark, leaf, and flower extracts of Cassia fistula on serum insulin and glycosylated hemoglobin (whole blood) in diabetic rats.

Experimental group	Insulin (IU/mL)	Glycosylated hemoglobin (%)
Normal control	130.5 ± 3.6	3.1 ± 0.1
Diabetic control	90.5 ± 2.1	9.0 ± 0.2
Glibenclamide	118.2 ± 3.6^c	4.8 ± 0.2^c
BME 250 mg/kg	103.5 ± 4.6	8.0 ± 0.2^b
BAE 250 mg/kg	98.3 ± 3.4	8.4 ± 0.2
BME 500 mg/kg	116.8 ± 3.4^c	5.3 ± 0.1^c
BAE 500 mg/kg	100.7 ± 2.9	8.1 ± 0.2^a
LME 250 mg/kg	104.8 ± 3.5^a	8.1 ± 0.2^a
LAE 250 mg/kg	98.2 ± 3.5	8.5 ± 0.3
LME 500 mg/kg	114.5 ± 2.0^c	5.9 ± 0.2^c
LAE 500 mg/kg	99.3 ± 2.9	8.3 ± 0.1
FME 250 mg/kg	98.5 ± 4.7	8.4 ± 0.2
FAE 250 mg/kg	93.3 ± 2.8	8.5 ± 0.3
FME 500 mg/kg	103.2 ± 3.0	8.3 ± 0.1
FAE 500 mg/kg	95.8 ± 4.6	8.4 ± 0.2

Values are mean ± SEM (𝑛=6).
𝑃 value: ^a<0.05, ^b<0.01, ^c<0.001 as compared with diabetic control group (by one-way ANOVA followed by Dunnett’s multiple comparison test).