Synthesis, Characterization, and Biological Activity of Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) Complexes of N-Thiophenoyl-N′-Phenylthiocarbohydrazide

Table 1

Analytical data and physical properties of the complexes N-thiophenoyl-N^′-phenylthiocarbohydrazide (H₂ TPTH).

Compound empirical formula	Colour/Yield (%)	Found (Calcd.) %						M.P. (°C)	𝜇 eff  (B.M.)
		M	C	H	N	S	N2H4
H2 TPTH C12H10N2S2O	Cream (60)	—	54.9 (55.0)	3.7 (3.8)	10.5 (10.7)	24.3 (24.4)	12.9 (13.0)	125	Diamag
[Mn(H TPTH)2] C24H18N4S3O3Mn	Yellow (55)	9.7 (9.8)	51.2 (51.3)	3.1 (3.2)	9.9 (10.0)	17.0 (17.1)	11.6 (11.7)	276	5.76
[Fe(H TPTH)2 (Et)]; C26H24N4S3O4Fe	Dirty yellow (45)	9.1 (9.2)	51.1 (51.3)	3.8 (3.9)	9.0 (9.2)	15.6 (15.8)	10.8 (10.8)	238	5.31
[Co(TPTH) (H2O)]; C12H12N2S2O3Co	Brick red (60)	16.4 (16.6)	40.4 (40.6)	3.3 (3.5)	7.7 (7.9)	17.8 (18.0)	9.3 (9.4)	>322	4.94
[Ni(TPTH) (H2O)2]; C12H12N2S2O3Ni	Dark green 55)	16.4 (16.5)	40.5 (40.6)	3.3 (3.4)	7.8 (7.9)	17.9 (18.0)	9.3 (9.4)	>364	3.06
[Cu(TPTH)]; C12H8N2S2OCu	Black (60)	19.5 (19.6)	44.4 (44.5)	2.3 (2.5)	8.6 (8.7)	19.7 (19.8)	10.3 (10.4)	282	1.98
[Zn(TPTH)]; C12H8N2S2OZn	White (45)	19.9 (20.1)	44.2 (44.3)	2.4 (2.5)	8.4 (8.6)	19.5 (19.7)	10.2 (10.3)	>363	Diamag
[Cd(H TPTH)2]; C24H18N4S3O3Cd	White (50)	18.1 (18.2)	46.5 (46.6)	2.8 (2.9)	9.0 (9.1)	15.3 (15.5)	10.5 (10.6)	256	Diamag