Research Article
Synthesis, Spectroscopic Characterization, and Biological Activities of Metal Complexes of 4-((4-Chlorophenyl)diazenyl)-2-((p-tolylimino)methyl)phenol
Table 8
The in vitro antimicrobial activity of [CDTMP] and its metal(II) complexes*.
| Compound | Concentration (μgmL−1) | Zone of inhibition (in mm) | E. coli | S. aureus | P. aeruginosa | A. niger | C. albicans |
| CDTMP () | 5 | 9 | 9 | 10 | R | 8 | 10 | 13 | 10 | 12 | 9 | 12 | 15 | 10 | 12 | R | 11 | 9 |
| VO(CDTMP)2] (
) | 5 | 16 | R | 14 | 15 | 16 | 10 | 19 | 20 | 19 | 20 | 19 | 15 | 25 | 27 | 22 | 26 | 27 |
| Mn(CDTMP)2·2H2O] (
) | 5 | 8 | 10 | 18 | 9 | R | 10 | 14 | 21 | R | 11 | R | 15 | R | R | 11 | R | R |
| Co(CDTMP)2·2H2O] (
) | 5 | R | 18 | 16 | 10 | 11 | 10 | 19 | 25 | 24 | 12 | 18 | 15 | 24 | 29 | 27 | 21 | 23 |
| Ni(CDTMP)2·2H2O] (
) | 5 | R | 12 | R | 14 | 11 | 10 | 17 | 21 | 17 | 17 | 14 | 15 | 10 | 24 | 24 | 25 | 20 |
| Cu(CDTMP)2] (
) | 5 | 21 | 20 | 21 | 20 | 23 | 10 | 26 | 31 | 23 | 31 | 25 | 15 | 27 | 33 | 26 | 32 | 29 |
| Zn(CDTMP)2·2H2O] (
) | 5 | 7 | 5 | 7 | 7 | 5 | 10 | 12 | 10 | 10 | 10 | 7 | 15 | 15 | 20 | 15 | 12 | 15 |
| Standard | 5 | 5 | 5 | 5 | 2 | 2 | 10 | 7 | 7 | 7 | 5 | 5 | 15 | 9 | 9 | 9 | 7 | 7 |
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Standard (Amikacin and Ketoconozole). *Zone of inhibition in mm. Each value observed is within the error limits of ±2. R: resistant.
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