Journal of Chemistry / 2013 / Article / Tab 3

Research Article

RP-HPLC Analytical Method Development and Validation for Simultaneous Estimation of Three Drugs: Glimepiride, Pioglitazone, and Metformin and Its Pharmaceutical Dosage Forms

Table 3

Results for accuracy of the method.

Initial conc areaSol 1 area50% areaSol 1—50% area% Recovery

Sol 1Glimepiride146572642256382580239921453983399.2
Pioglitazone113024191739362561896211120400499.13
Metformin110723632005681490301061102670899.59

Initial conc areaSol 2 area75% areaSol 2—75% area% Recovery

Sol 2Glimepiride1465726426129857116303411449951698.92
Pioglitazone1130241920320163895400511366158100.56
Metformin11072363213653971014688911218508101.32

Initial conc areaSol 3 area100% areaSol 3—100% area% Recovery

Sol 3Glimepiride14657264293674811465726414710217100.36
Pioglitazone1130241922539487113024191123706899.42
Metformin11072363222496781107236311177315100.95

Initial conc areaSol 4 area125% areaSol 4—125% area% Recovery

Sol 4Glimepiride1465726432182741175673701461537199.71
Pioglitazone1130241928483584136185621122502299.32
Metformin1107236322950236118785931107164399.99

Initial conc areaSol 5 area150% areaSol 5—150%% Recovery

Sol 5Glimepiride14657264343628701954904414813826101.07
Pioglitazone1130241926320185151207151119947099.09
Metformin1107236323472537124165311105600699.85

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