RP-HPLC Analytical Method Development and Validation for Simultaneous Estimation of Three Drugs: Glimepiride, Pioglitazone, and Metformin and Its Pharmaceutical Dosage Forms

Table 5

% RSD at different flow rates.

	Retention times % RSD	Areas % RSD	Sample area % RSD
1.5 mL/min
Glimepiride	0.05	0.14	0.4
Pioglitazone	0.04	0.09	0.22
Metformin	0.06	0.52	0.22
1.9 mL/min
Glimepiride	0.07	0.69	0.14
Pioglitazone	0.03	0.05	0.01
Metformin	0	0.21	0.18