RP-HPLC Analytical Method Development and Validation for Simultaneous Estimation of Three Drugs: Glimepiride, Pioglitazone, and Metformin and Its Pharmaceutical Dosage Forms
Table 5
% RSD at different flow rates.
Retention times % RSD
Areas % RSD
Sample area % RSD
1.5 mL/min
Glimepiride
0.05
0.14
0.4
Pioglitazone
0.04
0.09
0.22
Metformin
0.06
0.52
0.22
1.9 mL/min
Glimepiride
0.07
0.69
0.14
Pioglitazone
0.03
0.05
0.01
Metformin
0
0.21
0.18
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