Synthesis of Substituted Thioureas and Their Sulfur Heterocyclic Systems of p-Amino Salicylic Acid as Antimycobacterial Agents

Table 2

Level 2 antituberculosis acidity assay results of 4, 9b, 13, and 14 (Level 2 assay).

Compd. no.	MIC/μg mL	IC50(μg mL)	SI
4	6.25	>10	1.5
9b	>12.5	—	—
13	>12.5	—	—
14	6.25	10	1.6

The assay was performed using BACTEC in which MIC of RMP was found as 0.125 μg/mL.