Table of Contents Author Guidelines Submit a Manuscript
Journal of Chemistry
Volume 2013 (2013), Article ID 890617, 8 pages
http://dx.doi.org/10.1155/2013/890617
Research Article

Synthesis and Antimicrobial Activities of Some New Heterocyclic Compounds Based on 6-Chloropyridazine-3(2H)-thione

1Riyadh Community College, King Saud University, P.O. Box 28095, Riyadh 11437, Saudi Arabia
2Chemistry Department, Faculty of Science, Jazan University, P.O. Box 2079, Jazan, Saudi Arabia
3Chemistry Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt
4Chemical Engineering Department, College of Engineering, King Saud University, P.O. Box 800, Riyadh 11421, Saudi Arabia

Received 21 January 2013; Revised 27 February 2013; Accepted 28 February 2013

Academic Editor: Patricia Valentao

Copyright © 2013 Nasser M. Abd El-Salam et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. G. Kandile, M. I. Mohamed, H. Zaky, and H. M. Mohamed, “Novel pyridazine derivatives: synthesis and antimicrobial activity evaluation,” European Journal of Medicinal Chemistry, vol. 44, no. 5, pp. 1989–1996, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Asif, A. Singh, and L. Ratnakar, “Antimicrobial agents: brief study of pyridazine derivatives against some phathogenic microrganisms,” Journal of Pharmacy Research, vol. 4, no. 3, pp. 664–667, 2011. View at Google Scholar
  3. A. Benmoussa, J. El harti, M. Ansar et al., “Synthesis and antimicrobial properties of some pyridazin-3-thiones derivatives,” International Journal of PharmTech Research, vol. 4, no. 4, pp. 1591–1594, 2012. View at Google Scholar
  4. I. I. Mangalagiu, “Recent achievements in the chemistry of 1,2-diazines,” Current Organic Chemistry, vol. 15, no. 5, pp. 730–752, 2011. View at Publisher · View at Google Scholar
  5. D. Mantu, M. C. Luca, C. Moldoveanu, G. Zbancioc, and I. I. Mangalagiu, “Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II,” European Journal of Medicinal Chemistry, vol. 45, no. 11, pp. 5164–5168, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. R. M. Butnariu and I. I. Mangalagiu, “New pyridazine derivatives: synthesis, chemistry and biological activity,” Bioorganic and Medicinal Chemistry, vol. 17, no. 7, pp. 2823–2829, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Drochioiu, V. Sunel, C. Oniscu, C. Basu, and M. Murariu, “The breakdown of plant biostructure followed by amino acids determination,” Romanian Biotechnological Letters, vol. 6, no. 2, pp. 155–165, 2001. View at Google Scholar
  8. R. M. Butnariu, M. D. Caprosu, V. Bejan et al., “Pyridazine and phthalazine derivatives with potential antimicrobial activity,” Journal of Heterocyclic Chemistry, vol. 44, no. 5, pp. 1149–1152, 2007. View at Google Scholar · View at Scopus
  9. S. Dima, M. Caprosu, M. Ungureanu, G. Grosu, and M. Petrovanu, “Antimicrobial and antifungical activity of some new 1-methyl-phtalazinium compounds,” Annales Pharmaceutiques Francaises, vol. 57, no. 5, pp. 415–416, 1999. View at Google Scholar · View at Scopus
  10. X. Han, Y. H. Hong, Z. H. U. You Quan, Z. X. Mao LIU Bim, H. U. Fang Zhong, and Y. H. Zheng, “Synthesis and herbicidal activities of novel 4-(3-trifluoromethylphenyl)-2H-pyridazin-3-one derivatives,” Science China Chemistry, vol. 53, no. 1, pp. 157–166, 2010. View at Publisher · View at Google Scholar
  11. H. M. Refaat, O. M. Khalil, and H. H. Kadry, “Synthesis and anti-inflammatory activity of certain piperazinylthienylpyridazine derivatives,” Archives of Pharmacal Research, vol. 30, no. 7, pp. 803–811, 2007. View at Google Scholar · View at Scopus
  12. C. Liljebris, J. Martinsson, L. Tedenborg et al., “Synthesis and biological activity of a novel class of pyridazine analogues as non-competitive reversible inhibitors of protein tyrosine phosphatase 1B (PTP1B),” Bioorganic and Medicinal Chemistry, vol. 10, no. 10, pp. 3197–3212, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. R. B. Tucaliuc, I. M. Risca, G. Drochioiu, and I. Mangalagiu, “Biological effect of some new pyridazine derivatives on wheat in germination experiments,” Romanian Biotechnological Letters, vol. 13, no. 4, pp. 3837–3842, 2008. View at Google Scholar · View at Scopus
  14. T. Ishikawa, Y. Iizawa, K. Okonogi, and A. Miyake, “Studies on Anti-MRSA parenteral cephalosporins I. Synthesis and antibacterial activity of 7,” Journal of Antibiotics, vol. 53, no. 10, pp. 1053–1070, 2000. View at Google Scholar · View at Scopus
  15. C. Almansa, A. F. De Arriba, F. L. Cavalcanti et al., “Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a]pyrimidines,” Journal of Medicinal Chemistry, vol. 44, no. 3, pp. 350–361, 2001. View at Google Scholar
  16. G. B. Barlin, L. P. Davies, and P. W. Harrison, “Imidazo[1,2-b]pyridazines. XXI. Syntheses of some 3-acylaminomethyl-6-(chloro and iodo)-2-(substituted phenyl)-imidazo[1,2-b]pyridazines and -imidazo[1,2-a]pyridines and their interaction with central and mitochondrial benzodiazepine,” Australian Journal of Chemistry, vol. 50, no. 1, pp. 61–68, 1997. View at Publisher · View at Google Scholar
  17. H. M. Faidallah, K. A. Khan, and M. S. I. Makki, “Synthesis and biological evaluation of new fused isoxazolo[4,5-d]pyridazine derivatives,” Journal of the Chinese Chemical Society, vol. 58, no. 2, pp. 191–198, 2011. View at Google Scholar · View at Scopus
  18. N. F. Abd El-Ghaffar, M. K. Mohamed, M. S. Kadah, A. M. Radwan, G. H. Said, and S. N. Abd el Al, “Synthesis and anti-tumor activities of some new pyridazinones containing the 2-phenyl-1H-indolyl moiety,” Journal of Chemical and Pharmaceutical Research, vol. 3, no. 3, pp. 248–259, 2011. View at Google Scholar · View at Scopus
  19. M. H. Sherif, G. A. Ahmed, A. A. Elbahnasawy, and E. O. Helal, “Chemical studies on 3,6-dichloropyridazine,” Journal of American Science, vol. 6, no. 11, pp. 570–574, 2010. View at Google Scholar
  20. N. M. Abd El-Salam, Z . Y. Al-Shoaibi, and G. A. Ahmed, “Chemical studies on 3,6-dichloropyridazine (part 2),” E-Journal of Chemistry, vol. 8, no. 4, pp. 1944–1950, 2011. View at Publisher · View at Google Scholar
  21. Y. L. Nene and P. N. Thapliyal, Fungicides in Plant Disease Control, IBH, New Delhi, India, 1982.