The Extracts of Some Marine Invertebrates and Algae Collected off the Coast Waters of Vietnam Induce the Inhibitory Effects on the Activator Protein-1 Transcriptional Activity in JB6 Cl41 Cells

Table 1

The effects of the extracts of the marine invertebrates and alga on AP-1-dependent transcriptional activity in JB6 Cl41 cells.

Num.*	Name^x	Conc.^£ mg/mL	AP-1^¥
O14-34	Callyspongia sp.	0.6	103
O15-34	Oscarella sp.	0.5	94
O16-34	Dysidea sp.	0.5	100
O17-34	Mycale sp.	0.5	134
O18-34	Chondrilla sp.	0.6	110
O19-34	Monanchora sp.	0.125 (0.24)**	40
O20-34	Haliclona sp.	0.6	96
O21-34	Spirastrella sp.	0.4	111
O22-34	Ascidian unidentified	0.8	80
O23-34	Petrosia sp.	0.8	64
O24-34	Demospongiae, unidentified	0.6	88
O25-34	Spirastrella sp.	0.6	41
O26-34	Callyspongia sp.	0.5	71
O27-34	Spongia sp.	0.5	98
O28-34	Mycale sp.	0.8	106
O29-34	Callyspongia sp.	0.6	101
O30-34	Chondrilla sp.	0.6	89
O31-34	Alga unidentified	0.5	98
O33-34	Callyspongia sp.	0.5	89
O34-34	Callyspongia sp.	0.5	70
O35-34	Xestospongia sp.	0.6	29
O36-34	Spongia sp.	0.5	35
O37-34	Spirastrella sp.	0.5	122
O38-34	Demospongiae, Haplosclerida, fam. unidentified	0.5	90
O41-34	Phakellia sp.	0.7	59
O42-34	Halichondria sp.	0.5	74
O43-34	Halichondria sp.	0.4	125
O44-34	Haliclona sp.	0.6	105
O45-34	Halichondria sp.	0.6	75
O46-34	Haliclona sp.	0.6	93
O47-34	Ascidian unidentified	0.6	95
O48a-34	Ascidian unidentified	0.8	79
O48b-34	Ascidian unidentified	0.8	96
O49-34	Echinoidea unidentified	0.8	105
O50-34	Pennatulacea unidentified	0.5	91
O52-34	Alga unidentified	1.0	95
O53-34	Alga unidentified	0.6	76
O54-34	Alga unidentified	0.6	89
O55-34	Alga unidentified	0.7	93
O56-34	Alga unidentified	0.5	169
O57-34	Petrosia sp.	0.5	105
O58-34	Demospongiae unidentified	0.125 (0.27)**	19
O59-34	Haliclona sp.	0.8	74
O60-34	Pachastrella sp.	0.0625 (0.17)**	47
O61-34	Spirastrella sp.	0.5	73
O62-34	Spongia sp.	0.6	71
O63-34	Spongia sp.	0.5	102
O64-34	Stelletta sp.	0.5	62
O65-34	Spirastrella sp.	0.25 (0.35)**	52
O66-34	Dysidea sp.	0.125	77
O67-34	Spongia sp.	0.6	84
O68-34	Algae unidentified	0.5	67
O69-34	Opistobranchia unidentified	0.25	88
O70-34	Opistobranchia unidentified	0.125 (0.22)**	121
O71-34	Opistobranchia unidentified	0.8	96
O72-34	Opistobranchia unidentified	0.5	149
O73-34	Spongia sp.	0.0625 (0.1)**	137
O74-34	Myxilla sp.	0.125 (0.23)**	14
O75-34	Spirastrella sp.	0.4	108
O76-34	Xestospongia sp.	0.5	117
O77-34	Stelletta sp.	0.0625	91
O78-34	Spongia sp.	0.25 (0.54)**	38
O79-34	Callyspongia sp.	0.5	108
O81-34	Gorgonian gen unidentified	0.5	35
O82-34	Gorgonian gen unidentified	0.25	104
O83-34	Ascidia	0.6	91
O84-34	Haliclona sp.	0.6	74
O85-34	Spirastrella sp.	0.8	60
O86-34	Halichondria sp.	0.8	63
O87-34	Spongia sp.	0.8	60
O88-34	Xestospongia sp.	0.6	109
O89-34	Clathria sp.	0.8	105
O90-34	Ascidian unidentified	1.0	105
O92-34	Spongia sp.	0.6	93
O93-34	Spirastrella sp.	0.5	124
O94-34	Spongia sp.	0.6	77
O95-34	Spongia sp.	0.6	105
O98-34	Crinoidea	0.6	71
O99-34	Demospongiae, unidentified	0.8	93
O100-34	Demospongiae, unidentified	0.8	87
O101-34	Demospongiae, unidentified	0.25 (0.4)**	127
O102-34	Spirastrella sp.	0.5	84
O103-34	Petrosia sp.	0.5	54
O104-34	Halichondria sp.	0.5	104
O105-34	Alga unidentified	0.25	99
O106-34	Alga unidentified	0.0625 (0.11)**	169
O107-34	Alga unidentified	0.6	144
O115-34	Crinoidea	0.25 (0.42)**	73
O117-34	Nudibranchia unidentified	0.25 (0.37)**	77
O119-34	Spirastrella sp.	0.6	118
O120-34	Haliclona sp.	0.6	88
O121-34	Demospongiae unidentified	0.6	111
O122-34	Spongia sp.	0.5	38
O123-34	Callyspongia sp.	0.0625	101
O124-34	Axinella sp.	0.6	52
O125-34	Aplysina sp.	0.6	60
O126-34	Spongia sp.	0.6	57
O127-34	Spongia sp.	0.0625 (0.16)**	46
O129-34	Crinoidea unidentified	0.6	84
O130-34	Crinoidea unidentified	0.5	90
O131-34	Crinoidea unidentified	0.125	83
O132-34	Nudibranchia unidentified	0.0625	84
O133-34	Ascidian unidentified	0.25 (0.37)**	73
O134-34	Haliclona sp.	0.0625	110
O135-34	Callyspongia sp.	0.5	135
O136-34	Spongia sp.	0.5	79
O137-34	Demospongiae; unidentified	0.25	84
O140-34	Spongia sp.	0.8	41
O141-34	Clathria sp.	0.8	63
O145-34	Callyspongia sp.	0.8	43
O146-34	Axinella sp.	0.6	33
O149-34	Suberites sp.	0.8	83
O152-34	Lithistida unidentified	0.8	67
O153-34	Halichondria sp.	0.8	102
O154-34	Penares sp.	0.25 (0.34)**	37
O155-34	Petrosia sp.	0.8	67
O156-34	Pheronema raphanus	0.0625	90
O157-34	Pachastrella sp.	0.8	49
O158-34	Lithistida unidentified	0.8	75
O159-34	Geodia sp.	0.125	98
O160-34	Demospongiae unidentified	0.8	55
O162-34	Halichondria sp.	0.8	60
O163-34	Spirastrella sp.	0.5	101
O165-34	Petrosia sp.	0.8	53
O167-34	Rhabdastrella globostellata	0.5	37
O168-34	Petrosia sp.	0.125	81
O169-34	Halichondria sp.	0.25 (0.48)**	36
O170-34	Acanthodendrilla sp.	0.0625 (0.1)**	53
O171-34	Callyspongia sp.	0.8	30
O172-34	Carteriospongia sp.	0.0625 (0.11)**	19
O173-34	Carteriospongia sp.	0.25 (0.32)**	76
O174-34	Axinella sp.	0.25 (0.41)**	33
O175-34	Halichondria sp.	0.25 (0.33)**	66
O176-34	Petrosia sp.	0.125	110
O177-34	Spongia sp.	0.125 (0.19)**	54
O178-34	Petrosia sp.	0.8	56
O179-34	Hyalonema sp.	0.25	80
O181-34	Porifera, Lithistida unidentified	0.5	43
O186-34	Porifera, Calcarea, unidentified	0.6	55
O187-34	Callyspongia sp.	0.0625	101
O188-34	Agelas sp.	0.8	50
O189-34	Axinella sp.	0.0625 (0.16)**	67
O192-34	Agelas sp.	0.8	47
O193-34	Petrosia sp.	0.5	42
O194-34	Amphimedon sp.	0.25 (0.39)**	42
O196-34	Spongia sp.	0.125 (0.23)**	60
O197-34	Axinella sp.	0.5	60
O198-34	Plakina sp.	0.5	41

∗The number of the voucher specimen.
^xSystematical name of the specimen.
^£Concentration of the extract dry residue in the MEM.
^¥AP-1-dependent transcriptional activity, percentage of the control.
**IC₅₀.