Research Article
Synthesis and Bioevaluation of Novel Imatinib Base Derivatives via 1,1′-Carbonyldiimidazole Catalyst
Table 2
In vitro antibacterial and antifungal activities of synthesized compounds.
| | Diameter of inhibition zone (mm) % inhibition | B. subtilis | S. aureus | X. malvacearum | E. coli | F. oxysporum |
| 8a | 12 | 14 | 13 | 12 | 45.6 | 8b | 14 | 11 | 11 | 12 | 47.2 | 8c | 13 | 12 | 11 | 11 | 51.3 | 8d | 11 | 17 | 11 | 13 | 52.7 | 8e | 11 | 14 | 12 | 13 | 41.9 | 8f | 13 | 15 | 14 | 14 | 44.6 | 8g | 12 | 11 | 13 | 13 | 45.2 | 8h | 11 | 12 | 13 | 13 | 43.2 | 8i | 11 | 11 | 12 | 12 | 41.1 | 8j | 13 | 15 | 16 | 14 | 56.1 | 8k | 11 | 12 | 13 | 14 | 48.3 | Streptomycin | 18 | 20 | 18 | 19 | — | Nystatin | — | — | — | — | 85.2 |
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