Table of Contents Author Guidelines Submit a Manuscript
Journal of Chemistry
Volume 2013, Article ID 915762, 4 pages
http://dx.doi.org/10.1155/2013/915762
Research Article

Separation and Identification of Furocoumarin in Fruits of Heracleum candicans DC. by HPTLC

Pharmacognosy and Ethnopharmacology Division, CSIR-National Botanical Research Institute, Lucknow 226003, India

Received 31 May 2013; Revised 1 August 2013; Accepted 2 August 2013

Academic Editor: Miguel Herrero

Copyright © 2013 A. K. S. Rawat et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. N. Chopra, I. C. Chopra, and B. S. Verma, Supplement To Glossary of Indian Medicinal Plants, CSIR, New Delhi, India, 1969.
  2. Y. Nath, B. Nazir, and K. L. Handa, “Medicinal importance of Heracleum,” Indian Journal of Pharmaceutical, vol. 23, pp. 303–304, 1961. View at Google Scholar
  3. H. Matsuda, N. Hirata, Y. Kawaguchi et al., “Melanogenesis stimulation in murine B16 melanoma cells by umberiferae plant extracts and their coumarin constituents,” Biological and Pharmaceutical Bulletin, vol. 28, no. 7, pp. 1229–1233, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Bal-Tembe, D. D. Joshi, and A. D. Lakdawala, “Isolation of the anti-inflammatory principle of Heracleum candicans,” Indian Journal of Chemistry B, vol. 35, no. 5, pp. 518–519, 1996. View at Google Scholar · View at Scopus
  5. M. Bandhopadhyay, S. B. Malik, and T. R. Seshadri, “Synthesis of New Cou­marin Components of Heracleum candicans,” Indian Journal of Chemistry, vol. 11, pp. 410–412, 1973. View at Google Scholar
  6. Y. N. Sharma, A. Zaman, and A. R. Kidwai, “Chemical examination of Heracleum candicans-I. Isolation and structure of a new furocoumarin-heraclenin,” Tetrahedron, vol. 20, no. 1, pp. 87–90, 1964. View at Google Scholar · View at Scopus
  7. M. Doi, T. Nakamori, M. Shibano, M. Taniguchi, N.-H. Wang, and K. Baba, “Candibirin A, a furanocoumarin dimer isolated from Heracleum candicans WALL,” Acta Crystallographica Section C, vol. 60, no. 11, pp. o833–o835, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. Y. N. Sharma, A. Zaman, A. R. Kidwai, R. B. Bates, and V. P. Thalacker, “Coumarin constituents of Heracleum candicans-III,” Tetrahedron, vol. 22, no. 9, pp. 3221–3225, 1966. View at Google Scholar · View at Scopus
  9. D. J. Wagstaff, “Dietary exposure to furocoumarins,” Regulatory Toxicology and Pharmacology, vol. 14, no. 3, pp. 261–272, 1991. View at Publisher · View at Google Scholar
  10. L. Q. Guo and Y. Yamazoe, “Inhibition of cytochrome P450 by furanocoumarins in grapefruit juice and herbal medicines,” Acta pharmacologica Sinica, vol. 25, no. 2, pp. 129–136, 2004. View at Google Scholar
  11. M. J. Ashwood-Smith, G. A. Poulton, M. Barker, and M. Mildenberger, “5-Methoxypsoralen, an ingredient in several suntan preparations, has lethal, mutagenic and clastogenic properties,” Nature, vol. 285, no. 5764, pp. 407–409, 1980. View at Google Scholar · View at Scopus
  12. A. Baumgart, M. Schmidt, H.-J. Schmitz, and D. Schrenk, “Natural furocoumarins as inducers and inhibitors of cytochrome P450 1A1 in rat hepatocytes,” Biochemical Pharmacology, vol. 69, no. 4, pp. 657–667, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. I. M. Schmitt, S. Chimenti, and F. P. Gasparro, “Psoralen-protein photochemistry: a forgotten field,” Journal of Photochemistry and Photobiology B, vol. 27, no. 2, pp. 101–107, 1995. View at Publisher · View at Google Scholar · View at Scopus
  14. G. M. Devagiri, R. Chand, J. M. Singh, and G. S. Pujar, “Spectrophotometric determination of furocoumarin bitter principles from the roots of Heracleum candicans Wall,” Indian Journal of Chemistry B, vol. 35, no. 8, pp. 878–879, 1996. View at Google Scholar · View at Scopus
  15. P. K. Mukherjee, “Problems and prospects for the GMP in herbal drugs in Indian systems of medicine. Drug information,” Drug Information Journal, vol. 63, no. 3, pp. 635–644, 2002. View at Google Scholar
  16. P. K. Mukherjee, Quality Control of Herbal Drugs-An Approach To Evaluation of Botanicals, Business Horizons, New Delhi, India, 2002.
  17. R. Govindarajan, D. P. Singh, A. P. Singh, M. M. Pandey, and A. K. S. Rawat, “A validated HPLC method for quantification and optimization of furocoumarins in different extracts of fruits of Heracleum candicans,” Chromatographia, vol. 66, no. 5-6, pp. 401–405, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Rastogi, M. M. Pandey, and A. K. S. Rawat, “Determination of heraclenin and heraclenol in Heracleum candicans D.C. by TLC,” Chromatographia, vol. 66, no. 7-8, pp. 631–634, 2007. View at Publisher · View at Google Scholar · View at Scopus