Table of Contents Author Guidelines Submit a Manuscript
Journal of Chemistry
Volume 2013, Article ID 925439, 9 pages
http://dx.doi.org/10.1155/2013/925439
Research Article

Synthesis and Antimicrobial Evaluation of Some Novel Trisubstituted s-Triazine Derivatives Based on Isatinimino, Sulphonamido, and Azacarbazole

Department of Chemistry, Banasthali University, Banasthali 304022, India

Received 20 December 2011; Accepted 3 May 2012

Academic Editor: Dexin Kong

Copyright © 2013 Sonika Jain et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. P. Raval, A. R. Rai, and N. H. Patel, “Synthesis and in vitro antimicrobial activity of N′-(4-(arylamino)-6-(pyridin-2-ylamino)-1,3,5-triazin-2-yl)benzohydrazide,” International Journal of ChemTech Research, vol. 3, no. 1, pp. 616–620, 2009. View at Google Scholar
  2. S. Nishigaki, F. Yoneda, and K. Morinaga, “Synthetic antibacterials. I. Nitrofurylvinyl-s-triazine derivatives,” Journal of Medicinal Chemistry, vol. 12, no. 1, pp. 39–42, 1969. View at Google Scholar
  3. L. D. S. Yadav, K. N. Shukla, R. Dwivedi, and H. Singh, “Synthesis of new 1,3,4-oxadiazolo [3, 2-a]-s-triazine-5,7-dithiones and the dithionone analogues as potential antifungal agents,” Indian Journal of Pharmaceutical Sciences, vol. 54, no. 1, pp. 33–37, 1992. View at Google Scholar · View at Scopus
  4. D. H. Mahajan, C. Pannecouque, E. de Clercq, and K. H. Chikhalia, “Synthesis and studies of new 2-(coumarin-4-yloxy)-4,6-(substituted)-s-triazine derivatives as potential anti-HIV agents,” Archiv der Pharmazie, vol. 342, no. 5, pp. 281–290, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. S. C. Yaguchi, Y. Chin Fukui , I. Koshimizu et al., “Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor,” Journal of the National Cancer Institute, vol. 98, no. 8, pp. 545–556, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. V. K. Pandey, S. Tusi, Z. Tusi, M. Joshi, and S. Bajpai, “Synthesis and biological activity of substituted 2,4,6-s-triazines,” Acta Pharmaceutica, vol. 54, no. 1, pp. 1–12, 2004. View at Google Scholar
  7. A. Agrawal, K. Shrivastav, S. K. Puri, and M. S. Chauhan, “Syntheses of 2,4,6-trisubstituted triazines as antimalarial agents,” Bioorganic and Medicinal Chemistry Letters, vol. 15, no. 3, pp. 531–533, 2005. View at Google Scholar
  8. G. S. Singh, T. Singh, and R. Lakhan, “Synthesis, 13C NMR and anticonvulsant activity of new isatin-based spiroazetidinones,” Indian Journal of Chemistry B, vol. 36, no. 10, pp. 951–954, 1997. View at Google Scholar
  9. F. D. Popp and H. Pajouhesh, “Potential anticonvulsant. IV: Condensation of isatin with benzoylacetone and isopropyl /methyl ketones,” Journal of Pharmaceutical Sciences, vol. 71, pp. 1052–1054, 1982. View at Google Scholar
  10. S. K. Bhattacharya and A. Chakrabarti, “Dose-related proconvulsant and anticonvulsant activity of isatin, a putative biological factor, in rats,” Indian Journal of Experimental Biology, vol. 36, no. 1, pp. 118–121, 1998. View at Google Scholar
  11. K. V. Sujith, J. N. Rao, P. Shetty, and B. Kalluraya, “Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety,” European Journal of Medicinal Chemistry, vol. 44, no. 9, pp. 3697–3702, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. C. T. Supuran, A. Casini, and A. Scozzafava, “Protease inhibitors of the sulfonamide type: anticancer, antiinflammatory, and antiviral agents,” Medicinal Research Reviews, vol. 23, no. 5, pp. 535–558, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Scozzafava, T. Owa, A. Mastrolorenzo, and C. T. Supuran, “Anticancer and antiviral sulfonamides,” Current Medicinal Chemistry, vol. 10, no. 11, pp. 925–953, 2003. View at Publisher · View at Google Scholar
  14. J. Y. Winum, A. Scozzafava, J. L. Montero, and C. T. Supuran, “Therapeutic potential of sulfamides as enzymes inhibitors,” Medicinal Research Reviews, vol. 26, no. 6, pp. 767–792, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. K. Isik and K. Özdemir, “Antimicrobial activity screening of some sulfonamide derivatives on some Nocardia species and isolates,” Microbiological Research, vol. 164, no. 1, pp. 49–58, 2009. View at Publisher · View at Google Scholar
  16. M. R. Burns, S. A. Jenkins, M. R. Kimbrell et al., “Polycationic sulfonamides for the sequestration of endotoxin,” Journal of Medicinal Chemistry, vol. 50, no. 4, pp. 877–888, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. L. M. Werbel, M. Angelo, D. W. Fry, and D. F. Worth, “Basically substituted ellipticine analogues as potential antitumor agents,” Journal of Medicinal Chemistry, vol. 29, no. 7, pp. 1321–1322, 1986. View at Google Scholar · View at Scopus
  18. R. D. Biljana, S. R. Niko, S. D. Vidoslav, R. D. Vukicević, and R. M. Palić, “Synthesis and antimicrobial activity of new 4-heteroarylamino coumarin derivatives containing nitrogen and sulfur as heteroatoms,” Molecules, vol. 15, no. 4, pp. 2246–2256, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. A. M. Carlos, M. T. Nuno, and A. R. Andreia, “Synthesis of 2,4,6-Tri-substituted-1,3,5-Triazines,” Molecules, vol. 11, pp. 81–102, 2006. View at Google Scholar
  20. F. R. Japp and F. Klingemann, “Ueber die constitution einiger sogenannten gemischten azoverbindungen,” Liebigs Annalen der Chemie, vol. 247, no. 2, pp. 190–225, 1888. View at Google Scholar