Ionic-Liquid-Mediated MacMillan’s Catalyst for Diels-Alder Reaction

Table 3

[bmim][NTf₂] mediated MacMillan’s imidazolidinone catalyst 1 catalysed, Diels-Alder reaction of various dienes with dienophiles.

Entry	Diene	Dienophiles	Yield^a (%)	endo : 𝑒𝑥𝑜^b	ee (%)^c
(1)			98	19 : 1	97
(2)			90	1.5 : 1	92
(3)			97	3 : 1	96
(4)			85	1.5 : 1	97
(5)			95	49 : 1	98
(6)			98	99 : 1	95
(7)			99	1.1 : 1	78
(8)			88	1.1 : 1	88
(9)			90	1 : 1	89
(10)			99	1.2 : 1	92

^aIsolated yield, ^bendo : exo ratio was determined by ¹H NMR crude reaction product, ^cee% or was determined by HPLC or GC analysis.