3D-QSAR and Docking Studies of a Series of β-Carboline Derivatives as Antitumor Agents of PLK1

Figure 5

Visual inspection of variables to identify the most discriminative ones. Red and blue boxes include active and inactive compounds, respectively. The numbers written in red represent the variables which have a high positive impact on antitumor activity and the variables with a significant negative impact are written in blue. If a variable is present (✓) or absent (—) in a compound as expected, the relative box is highlighted in green; otherwise it is highlighted in yellow.