3D-QSAR and Docking Studies of a Series of β-Carboline Derivatives as Antitumor Agents of PLK1
Figure 7
Schematic representation of the results revealed by the present study. (a) As variables of 3D-QSAR model. Yellow, green, and blue circles represent hydrophobic (DRY), shape (TIP), and hydrogen bond acceptor (N1) regions, respectively. Red and blue lines represent the variables with positive and negative impact, respectively. (b) As structural requirements of -carboline derivatives as PLK1 inhibitors.
