Research Article
Pharmacokinetic Comparison of Isoalantolactone and Alantolactone in Rats after Administration Separately by Optimization of an UPLC-MS2 Method
Table 1
Precision and accuracy of QC samples in rat plasma (
).
| | Concentration | RSD (%) | RE (%) | | (ng/mL) | Intraday | Interday | Intraday | Interday |
| | Isoalantolactone | | | | | | 5 | 3.73 | 5.24 | −12.57 | −9.83 | | 50 | 2.41 | 3.59 | −10.86 | −9.23 | | 400 | 3.19 | 5.64 | −4.20 | 6.62 | | Alantolactone | | | | | | 5 | 4.25 | 9.57 | 10.90 | 14.53 | | 50 | 6.23 | 9.33 | 9.18 | −9.22 | | 400 | 7.06 | 7.56 | 2.78 | −6.13 |
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