Synthesis, Single Crystal X-Ray Structure, and Antimicrobial Activity of 6-(1,3-Benzodioxol-5-ylmethyl)-5-ethyl-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}pyrimidin-4(3<i>H</i>)-one

<table>Synthesis of the intermediate piperonylcarbonitrile<b> (4)</b>. Reagents and conditions: (i) NaBH<sub>4</sub>, methanol, RT, 18 h; (ii) SOCl<sub>2</sub>, RT, 18 h; (iii) NaCN, KI, DMF, RT, 18 h.</table>

Journal of Chemistry

sch1

Scheme 1

Scheme 1: Synthesis, Single Crystal X-Ray Structure, and Antimicrobial Activity of 6-(1,3-Benzodioxol-5-ylmethyl)-5-ethyl-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}pyrimidin-4(3<i>H</i>)-one 

Scheme 1 | Synthesis, Single Crystal X-Ray Structure, and Antimicrobial Activity of 6-(1,3-Benzodioxol-5-ylmethyl)-5-ethyl-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}pyrimidin-4(3H)-one 