Synthesis, Single Crystal X-Ray Structure, and Antimicrobial Activity of 6-(1,3-Benzodioxol-5-ylmethyl)-5-ethyl-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}pyrimidin-4(3H)-one

Scheme 2

Synthesis of the target compound 8. Reagents and conditions: (i) (1) Zn/THF, (2) K₂CO₃, and (3) HCl; (ii) (1) NH₂CSNH₂, NaOEt, ethanol, reflux, 24 h and (2) HCl; (iii) N-(2-chloroethyl) morpholine hydrochloride, K₂CO₃, DMF, RT, 18 h.