Research Article

Synthesis, Single Crystal X-Ray Structure, and Antimicrobial Activity of 6-(1,3-Benzodioxol-5-ylmethyl)-5-ethyl-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}pyrimidin-4(3H)-one

Table 5

The minimum inhibitory concentration (MIC, mol/mL) values for the target compound 8, ampicillin, and clotrimazole towards the test microorganisms.

Compound numberThe minimum inhibitory concentrations (MICs, mol/mL)*
Gram-positive bacteria Pathogenic fungi
Staphylococcus aureus Bacillus subtilis Bacillus cereus Candida albicans Aspergillus niger

80.06190.18590.18590.18590.1859
Ampicillin0.02580.02580.0258
Clotrimazole0.02610.0348

The lowest concentration of the test compound that inhibits the growth of microorganism ( mol/mL).