Research Article
Synthesis, Characterization, X-Ray Crystal Structure, and Antimicrobial Activity of 1,1′-(3,4-Diphenylthieno[2,3-b]thiophene-2,5-diyl)diethanone
Table 3
Antimicrobial activity of compound 4.
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Comp. number | Gram-positive bacteria | Gram-negative bacteria | Fungi | Staphylococcus pneumoniae | Bacillus subtilis | Pseudomonas aeruginosa | Escherichia coli | Aspergillus fumigatus | Candida albicans |
| 4 | 12.9 ± 0.63 | 13.2 ± 0.58 | NA |
10.8 ± 0.44 | 18.7 ± 0.36 | 16.9 ± 0.27 | Ampicillin | 23.8 ± 0.2 | 32.4 ± 0.3 | — | — | — | — | Gentamicin | — | — | 17.3 ± 0.1 | 19.9 ± 0.3 | — | — | Amphotericin B | — | — | — | — | 23.7 ± 0.1 | 25.4 ± 0.1 |
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Inhibition zones (mm). NA: no activity.
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