Review Article

188W/188Re Generator System and Its Therapeutic Applications

Table 2

The characteristics of the commercial 188W/188Re generators.

Institution/suppliersStrengthColumn materialSpecific activity of W-188Remarks

ORNL, TN, USA 9.25 GBq (250 mCi) to 111 GBq (3 Ci) cGMP system Alumina 148–185 GBq (4-5 Ci)/g >500 generators since 1986.

Dimitrovgrad, Russia 3.7–111 GBq (0.1–3 Ci) Sterile cGMP system Alumina 185 GBq (5 Ci)/g Regular production and supply.

IRE, Belgium Up to 55.4 GBq (1.5 Ci) Alumina 185 GBq (5 Ci)/g Generator is available with an automatic concentration module.

ITM AG, Germany Unknown Alumina 185 GBq (5 Ci)/g Regular production and supply.

Polatom, Poland 18.5 GBq (500 mCi) cGMP system Use of Tc column system 185 GBq (5 Ci)/g Regular production and supply.

IDB, Holland 3.7–18.5 GBq (100–500 mCi) Alumina Unknown Regular production and supply.