Pharmacological Profile of Quinoxalinone

Table 7

Antiviral activity of compounds 50a–h.

Compound	R3	ArSO2	IC50 (𝜇M)
50a	H	Quinoline-8-sulfonyl	0.98
50b	H	3-Cyanobenzene-1-sulfonyl	>100
50c	H	2-Methyloxycarbonylthiophene-3-sulfonyl	2.02
50d	CH3	Quinoline-8-sulfonyl	7.0
50e	CH3	4-Nitrobenzene-1-sulfonyl	>100
50f	CH3	3-Cyanobenzene-1-sulfonyl	55
50g	CH3	2-Methyloxycarbonylthiophene-3-sulfonyl	0.2
50h	CH3	2,5-Dichlorothiophene-3-sulfonyl	>100