Synthesis of Some New Pyrimidine-Azitidinone Analogues and Their Antioxidant, In Vitro Antimicrobial, and Antitubercular Activities

Table 4

The in vitro antioxidant activity of 7a–j in hydrogen peroxide (H₂O₂) method.

Compounds	Concentration (µg/mL)
	25	50	75	IC50
7a	61.05±0.85	63.84±1.58	68.22±1.07	20.47±1.23
7b	58.25±1.17	62.31±1.17	65.74±1.47	21.22±1.07
7c	60.26±1.06	63.48±1.27	67.84±1.57	20.71±0.54
7d	61.94±1.32	64.51±1.18	68.22±1.07	20.15±0.75
7e	45.02±0.88	47.38±1.17	50.44±1.27	27.75±0.65
7f	53.08±0.89	56.61±1.39	59.95±0.78	23.54±0.42
7g	51.37±1.16	54.03±0.86	58.12±0.97	24.33±1.04
7h	64.12±0.27	67.44±0.64	69.81±0.69	19.49±0.26
7i	66.25±1.15	69.53±1.31	71.68±0.60	18.85±0.60
7j	63.87±0.30	65.49±0.46	68.97±0.65	19.57±1.26
Ascorbic acid	76.41±0.18	78.60±0.33	82.39±0.61	16.31±0.31
Blank	—	—	—	—

(—) showed no scavenging activity. Values were the means of three replicates ± SD.