Synthesis of New [1,2,4]Triazolo[3,4-b][1,3,4]thiadiazines and Study of Their Anti-Candidal and Cytotoxic Activities

Table 1

Some properties of the synthesized compounds 5a–h.

Compound	Ar	Yield (%)	M.p. (°C)	Molecular formula	Molecular weight (g/mol)
5a	C6H5	50	295–297	C16H13N7S	335.38
5b	2-CH3-C6H5	60	288–290	C17H15N7S	349.41
5c	4-OCH3-C6H5	65	273–275	C17H15N7OS	365.41
5d	4-Br-C6H5	80	270–272	C16H12BrN7S	414.28
5e	4-Cl-C6H5	75	293–295	C16H12ClN7S	369.83
5f	4-F-C6H5	80	278–280	C16H12FN7S	353.37
5g	4-SO2NH2-C6H5	70	320–322	C16H14N8O2S2	414.46
5h	4-CH3-C6H5	60	290–292	C17H15N7S	349.41