Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery

<table>The obtained pharmacophore model (orange: RA, green: HBA_L, blue: HY, and grey: excluded volumes) showing (a) interfeature distances, (b) mapping of one of the most potent compounds, 7a, (c) mapping of the other most potent compound, 7n, and (d) mapping of the least active compound 5l.</table>

Journal of Chemistry

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Figure 6

Figure 6: Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery 

Figure 6 | Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery 