Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery

<table>Mapping of advanced UT antagonists on the obtained pharmacophore model; (a) SB-611812 (fit value: 6.811), (b) SB-657510 (fit value: 6.505), (c) palosuran (Fit value: 5.714), (d) SB-706375 (fit value: 5.555), and (e) SB-436811 (Fit value: 5.334).</table>

Journal of Chemistry

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Figure 7

Figure 7: Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery 

Figure 7 | Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery 